In a slow cooker or Dutch oven, combine the beef broth, water, oregano, basil, thyme, garlic powder, onion powder, black pepper, salt, and red wine vinegar.
Add the beef roast to the pot, making sure it is completely submerged in the liquid.
Cook on low heat for 8-10 hours, or until the beef is tender and can be easily shredded with a fork.
Remove the beef from the liquid and shred it with two forks. Return the shredded beef to the pot and stir to combine with the broth.
Serve the beef on crusty Italian rolls with sweet peppers or hot giardiniera.